Authors Gual P, Gilgenkrantz H, Lotersztajn S
American journal of physiology. Cell physiology Mar 2017
Structure activity relationship and optimization of N-(3-(2-aminothiazol-4-yl)aryl)benzenesulfonamides as anti-cancer compounds against sensitive and resistant cells.Authors Ronco C, Millet A, Plaisant M, Abbe P, Hamouda-Tekaya N, Rocchi S, Benhida R
Bioorganic & medicinal chemistry letters Mar 2017
Identification of cancer-associated missense mutations in hace1 that impair cell growth control and Rac1 ubiquitylation.Authors Andrio E, Lotte R, Hamaoui D, Cherfils J, Doye A, Daugaard M, Sorensen PH, Bost F, Ruimy R, Mettouchi A, Lemichez E
Scientific reports Mar 2017
[Autophagy, a key player in leukemogenesis and a therapeutic target in hematopoietic malignancies].Authors Jacquel A, Luciano F, Puissant A, Robert G, Auberger P
Medecine sciences : M/S Mar 2017
[Autophagy in chronic liver diseases: a friend rather than a foe?]Authors Gual P, Gilgenkrantz H, Lotersztajn S
Medecine sciences : M/S Mar 2017
The creatine kinase pathway is a metabolic vulnerability in EVI1-positive acute myeloid leukemia.Authors Fenouille N, Bassil CF, Ben-Sahra I, Benajiba L, Alexe G, Ramos A, Pikman Y, Conway AS, Burgess MR, Li Q, Luciano F, Auberger P, Galinsky I, DeAngelo DJ, Stone RM, Zhang Y, Perkins AS, Shannon K, Hemann MT, Puissant A, Stegmaier K
Nature medicine Mar 2017
Transfer of dysbiotic gut microbiota has beneficial effects on host liver metabolism.Authors Nicolas S, Blasco-Baque V, Fournel A, Gilleron J, Klopp P, Waget A, Ceppo F, Marlin A, Padmanabhan R, Iacovoni JS, Tercé F, Cani PD, Tanti JF, Burcelin R, Knauf C, Cormont M, Serino M
Molecular systems biology Mar 2017
Mammary adipocytes stimulate breast cancer invasion through metabolic remodeling of tumor cells.Authors Wang YY, Attané C, Milhas D, Dirat B, Dauvillier S, Guerard A, Gilhodes J, Lazar I, Alet N, Laurent V, Le Gonidec S, Biard D, Hervé C, Bost F, Ren GS, Bono F, Escourrou G, Prentki M, Nieto L, Valet P, Muller C
JCI insight Feb 2017
Autophagy, a key mechanism of oncogenesis and resistance in leukemia.Authors Auberger P, Puissant A
Blood Feb 2017
In Vitro and in Vivo Evaluation of Fully Substituted (5-(3-Ethoxy-3-oxopropynyl)-4-(ethoxycarbonyl)-1,2,3-triazolyl-glycosides as Original Nucleoside Analogues to Circumvent Resistance in Myeloid Malignancies.Authors Amdouni H, Robert G, Driowya M, Furstoss N, Métier C, Dubois A, Dufies M, Zerhouni M, Orange F, Lacas-Gervais S, Bougrin K, Martin AR, Auberger P, Benhida R
Journal of medicinal chemistry Feb 2017