List of publications

All the publications of the C3M teams.

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Metformin and cancer therapy.

Authors Bost F, Sahra IB, Le Marchand-Brustel Y, Tanti JF

Current opinion in oncology Jan 2012

Metformin, independent of AMPK, induces mTOR inhibition and cell-cycle arrest through REDD1.

Authors Ben Sahra I, Regazzetti C, Robert G, Laurent K, Le Marchand-Brustel Y, Auberger P, Tanti JF, Giorgetti-Peraldi S, Bost F

Cancer research May 2011

Inhibition of hedgehog signaling decreases proliferation and clonogenicity of human mesenchymal stem cells.

Authors Plaisant M, Giorgetti-Peraldi S, Gabrielson M, Loubat A, Dani C, Peraldi P

PloS one Feb 2011

Deficiency in the extracellular signal-regulated kinase 1 (ERK1) protects leptin-deficient mice from insulin resistance without affecting obesity.

Authors Jager J, Corcelle V, Grémeaux T, Laurent K, Waget A, Pagès G, Binétruy B, Le Marchand-Brustel Y, Burcelin R, Bost F, Tanti JF

Diabetologia Jan 2011

The combination of metformin and 2 deoxyglucose inhibits autophagy and induces AMPK-dependent apoptosis in prostate cancer cells.

Authors Ben Sahra I, Tanti JF, Bost F

Autophagy Jul 2010

The combination of metformin and 2-deoxyglucose inhibits autophagy and induces AMPK-dependent apoptosis in prostate cancer cells.

Authors Ben Sahra I, Tanti JF, Bost F

Autophagy Jul 2010

Apelin and APJ regulation in adipose tissue and skeletal muscle of type 2 diabetic mice and humans.

Authors Dray C, Debard C, Jager J, Disse E, Daviaud D, Martin P, Attané C, Wanecq E, Guigné C, Bost F, Tanti JF, Laville M, Vidal H, Valet P, Castan-Laurell I

American journal of physiology. Endocrinology and metabolism Jun 2010

Metformin in cancer therapy: a new perspective for an old antidiabetic drug?

Authors Ben Sahra I, Le Marchand-Brustel Y, Tanti JF, Bost F

Molecular cancer therapeutics May 2010

Targeting cancer cell metabolism: the combination of metformin and 2-deoxyglucose induces p53-dependent apoptosis in prostate cancer cells.

Authors Ben Sahra I, Laurent K, Giuliano S, Larbret F, Ponzio G, Gounon P, Le Marchand-Brustel Y, Giorgetti-Peraldi S, Cormont M, Bertolotto C, Deckert M, Auberger P, Tanti JF, Bost F

Cancer research Mar 2010

Insulin induces REDD1 expression through hypoxia-inducible factor 1 activation in adipocytes.

Authors Regazzetti C, Bost F, Le Marchand-Brustel Y, Tanti JF, Giorgetti-Peraldi S

The Journal of biological chemistry Dec 2009