Liste des publications

Toutes les publications des équipes du C3M.

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Metformin in cancer therapy: a new perspective for an old antidiabetic drug?

Auteurs Ben Sahra I, Le Marchand-Brustel Y, Tanti JF, Bost F

Molecular cancer therapeutics May 2010

Targeting cancer cell metabolism: the combination of metformin and 2-deoxyglucose induces p53-dependent apoptosis in prostate cancer cells.

Auteurs Ben Sahra I, Laurent K, Giuliano S, Larbret F, Ponzio G, Gounon P, Le Marchand-Brustel Y, Giorgetti-Peraldi S, Cormont M, Bertolotto C, Deckert M, Auberger P, Tanti JF, Bost F

Cancer research Mar 2010

Tpl2 kinase is upregulated in adipose tissue in obesity and may mediate interleukin-1beta and tumor necrosis factor-{alpha} effects on extracellular signal-regulated kinase activation and lipolysis.

Auteurs Jager J, Grémeaux T, Gonzalez T, Bonnafous S, Debard C, Laville M, Vidal H, Tran A, Gual P, Le Marchand-Brustel Y, Cormont M, Tanti JF

Diabetes Jan 2010

Insulin induces REDD1 expression through hypoxia-inducible factor 1 activation in adipocytes.

Auteurs Regazzetti C, Bost F, Le Marchand-Brustel Y, Tanti JF, Giorgetti-Peraldi S

The Journal of biological chemistry Déc 2009

Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy.

Auteurs Risson V, Mazelin L, Roceri M, Sanchez H, Moncollin V, Corneloup C, Richard-Bulteau H, Vignaud A, Baas D, Defour A, Freyssenet D, Tanti JF, Le-Marchand-Brustel Y, Ferrier B, Conjard-Duplany A, Romanino K, Bauché S, Hantaï D, Mueller M, Kozma SC, Thomas G, Rüegg MA, Ferry A, Pende M, Bigard X, Koulmann N, Schaeffer L, Gangloff YG

The Journal of cell biology Dec 2009

Cellular mechanisms of insulin resistance: role of stress-regulated serine kinases and insulin receptor substrates (IRS) serine phosphorylation.

Auteurs Tanti JF, Jager J

Current opinion in pharmacology Dec 2009

Helicobacter pylori counteracts the apoptotic action of its VacA toxin by injecting the CagA protein into gastric epithelial cells.

Auteurs Oldani A, Cormont M, Hofman V, Chiozzi V, Oregioni O, Canonici A, Sciullo A, Sommi P, Fabbri A, Ricci V, Boquet P

PLoS pathogens Oct 2009

The inflammatory receptor CD40 is expressed on human adipocytes: contribution to crosstalk between lymphocytes and adipocytes.

Auteurs Poggi M, Jager J, Paulmyer-Lacroix O, Peiretti F, Gremeaux T, Verdier M, Grino M, Stepanian A, Msika S, Burcelin R, de Prost D, Tanti JF, Alessi MC

Diabetologia Jun 2009

Involvement of TNF-alpha in abnormal adipocyte and muscle sortilin expression in obese mice and humans.

Auteurs Kaddai V, Jager J, Gonzalez T, Najem-Lendom R, Bonnafous S, Tran A, Le Marchand-Brustel Y, Gual P, Tanti JF, Cormont M

Diabetologia May 2009

The nitric oxide-donating derivative of acetylsalicylic acid, NCX 4016, stimulates glucose transport and glucose transporters translocation in 3T3-L1 adipocytes.

Auteurs Kaddai V, Gonzalez T, Bolla M, Le Marchand-Brustel Y, Cormont M

American journal of physiology. Endocrinology and metabolism Jul 2008